How It Works
Thymosin Alpha-1 (Tα1) acts on dendritic cells and T-cells to enhance immune surveillance. It stimulates T-cell maturation, increases natural killer cell activity, promotes dendritic cell differentiation, and modulates cytokine production. Uniquely, it balances the immune response — upregulating when needed and preventing overactivation. It activates toll-like receptors (TLR2, TLR9) and stimulates both Th1 and Th2 pathways.
Reconstitution Guide
Follow these steps to properly reconstitute Thymosin Alpha-1 for research use:
- Step 1: Swab the tops of both the peptide vial and bacteriostatic water vial with alcohol.
- Step 2: Draw your desired amount of BAC water (commonly 1–2 mL) into an insulin syringe.
- Step 3: Inject the water slowly into the peptide vial, aiming at the glass wall — not directly onto the powder.
- Step 4: Swirl the vial gently until fully dissolved — never shake.
- Step 5: Refrigerate at 36–46°F (2–8°C). Use within 4–6 weeks.
Use the dosing calculator to calculate your exact concentration (mcg per unit) and how many units to draw on your syringe.
Frequently Asked Questions
How does Thymosin Alpha-1 work? ▾
Thymosin Alpha-1 (Tα1) acts on dendritic cells and T-cells to enhance immune surveillance. It stimulates T-cell maturation, increases natural killer cell activity, promotes dendritic cell differentiation, and modulates cytokine production. Uniquely, it balances the immune response — upregulating when needed and preventing overactivation. It activates toll-like receptors (TLR2, TLR9) and stimulates both Th1 and Th2 pathways.
What are the key research findings? ▾
- Approved in 30+ countries for hepatitis B/C treatment (as Zadaxin)
- Enhanced vaccine response and immune function in immunocompromised patients
- Studied for adjunctive treatment in various cancers and chronic infections
- Excellent safety profile — does not cause immune overstimulation or autoimmune reactions
What is the typical dosing protocol? ▾
Standard dosing: 1.6 mg subcutaneously 2–3 times per week. Clinical protocols use 1.6 mg twice weekly for chronic conditions. Some intensive protocols use daily dosing for 2–4 weeks during acute immune challenges. Can be used long-term with excellent safety profile.
How should Thymosin Alpha-1 be stored? ▾
Unreconstituted powder should be stored in a freezer or refrigerator away from light and moisture. Once reconstituted with bacteriostatic water, refrigerate at 36–46°F (2–8°C) and use within 4–6 weeks. Never freeze reconstituted peptides.