MOTS-c

How It Works

MOTS-c is a 16-amino acid peptide that functions as a signaling molecule linking mitochondrial activity to nuclear gene expression. It activates AMPK, regulates metabolic homeostasis, and enhances cellular stress resistance. It has been called an "exercise mimetic" for its ability to activate pathways similar to physical exercise.

Key Research Findings

• Activates AMPK pathway, improving glucose metabolism and insulin sensitivity
• Shown to enhance exercise capacity and physical performance in studies
• Research suggests anti-aging properties through mitochondrial optimization
• May protect against metabolic stress and age-related metabolic decline

Common Research Protocols

Use our free dosing calculator to determine exact syringe units after reconstitution.

Reconstitution Guide

Follow these steps to properly reconstitute MOTS-c for research use:

• Step 1: Swab the tops of both the peptide vial and bacteriostatic water vial with alcohol.
• Step 2: Draw your desired amount of BAC water (commonly 1–2 mL) into an insulin syringe.
• Step 3: Inject the water slowly into the peptide vial, aiming at the glass wall — not directly onto the powder.
• Step 4: Swirl the vial gently until fully dissolved — never shake.
• Step 5: Refrigerate at 36–46°F (2–8°C). Use within 4–6 weeks.

Use the dosing calculator to calculate your exact concentration (mcg per unit) and how many units to draw on your syringe.

Frequently Asked Questions

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