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Thymosin Beta-4

Recovery Inflammatory Cardiac
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How It Works

Thymosin Beta-4 sequesters G-actin (monomeric actin), regulating actin polymerization which is essential for cell migration, proliferation, and differentiation. It promotes angiogenesis, reduces inflammation through NF-κB modulation, and activates cardiac progenitor cells. TB-500 is a synthetic fragment of Thymosin Beta-4 containing the active region, but full-length Tβ4 provides additional biological activities.

Key Research Findings

Common Research Protocols

Research Dosing Range
Loading phase: 2–5 mg subcutaneously twice weekly for 4–6 weeks. Maintenance: 2–5 mg once every 1–2 weeks. Often used interchangeably with TB-500 (its active fragment). Commonly stacked with BPC-157 for comprehensive healing protocols.

Use our free dosing calculator to determine exact syringe units after reconstitution.

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Reconstitution Guide

Follow these steps to properly reconstitute Thymosin Beta-4 for research use:

Use the dosing calculator to calculate your exact concentration (mcg per unit) and how many units to draw on your syringe.

Frequently Asked Questions

How does Thymosin Beta-4 work?
Thymosin Beta-4 sequesters G-actin (monomeric actin), regulating actin polymerization which is essential for cell migration, proliferation, and differentiation. It promotes angiogenesis, reduces inflammation through NF-κB modulation, and activates cardiac progenitor cells. TB-500 is a synthetic fragment of Thymosin Beta-4 containing the active region, but full-length Tβ4 provides additional biological activities.
What are the key research findings?
  • Promotes tissue repair across muscle, tendons, ligaments, skin, and cardiac tissue
  • Cardioprotective properties — activates cardiac progenitor cells after ischemia
  • Reduces fibrosis and scar formation in multiple tissue types
  • Currently in clinical trials for wound healing and cardiac repair applications
What is the typical dosing protocol?
Loading phase: 2–5 mg subcutaneously twice weekly for 4–6 weeks. Maintenance: 2–5 mg once every 1–2 weeks. Often used interchangeably with TB-500 (its active fragment). Commonly stacked with BPC-157 for comprehensive healing protocols.
How should Thymosin Beta-4 be stored?
Unreconstituted powder should be stored in a freezer or refrigerator away from light and moisture. Once reconstituted with bacteriostatic water, refrigerate at 36–46°F (2–8°C) and use within 4–6 weeks. Never freeze reconstituted peptides.

Need to Calculate Your Thymosin Beta-4 Dose?

Use our free reconstitution calculator for precise syringe measurements.

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