How It Works
GHRP-2 (pralmorelin) binds to the growth hormone secretagogue receptor (GHS-R1a) in the pituitary gland and hypothalamus. It stimulates a strong, dose-dependent GH release while also increasing ghrelin, cortisol, and prolactin to a moderate degree. It also inhibits somatostatin, the hormone that suppresses GH release, creating a dual mechanism for GH elevation.
Key Research Findings
- Produces the strongest GH release among the GHRP family of peptides
- Increases IGF-1, lean mass, and recovery markers in research
- Moderate appetite stimulation (less than GHRP-6, more than Ipamorelin)
- May slightly elevate cortisol and prolactin at higher doses
Common Research Protocols
Use our free dosing calculator to determine exact syringe units after reconstitution.
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Follow these steps to properly reconstitute GHRP-2 for research use:
- Step 1: Swab the tops of both the peptide vial and bacteriostatic water vial with alcohol.
- Step 2: Draw your desired amount of BAC water (commonly 1–2 mL) into an insulin syringe.
- Step 3: Inject the water slowly into the peptide vial, aiming at the glass wall — not directly onto the powder.
- Step 4: Swirl the vial gently until fully dissolved — never shake.
- Step 5: Refrigerate at 36–46°F (2–8°C). Use within 4–6 weeks.
Use the dosing calculator to calculate your exact concentration (mcg per unit) and how many units to draw on your syringe.
Frequently Asked Questions
- Produces the strongest GH release among the GHRP family of peptides
- Increases IGF-1, lean mass, and recovery markers in research
- Moderate appetite stimulation (less than GHRP-6, more than Ipamorelin)
- May slightly elevate cortisol and prolactin at higher doses
Need to Calculate Your GHRP-2 Dose?
Use our free reconstitution calculator for precise syringe measurements.
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