How It Works
Ipamorelin is a pentapeptide that selectively mimics ghrelin and binds to the growth hormone secretagogue receptor (GHS-R) in the pituitary gland. Unlike other GHRPs, it produces a very targeted GH release without significantly elevating cortisol, acetylcholine, prolactin, or aldosterone, resulting in fewer side effects.
Reconstitution Guide
Follow these steps to properly reconstitute Ipamorelin for research use:
- Step 1: Swab the tops of both the peptide vial and bacteriostatic water vial with alcohol.
- Step 2: Draw your desired amount of BAC water (commonly 1–2 mL) into an insulin syringe.
- Step 3: Inject the water slowly into the peptide vial, aiming at the glass wall — not directly onto the powder.
- Step 4: Swirl the vial gently until fully dissolved — never shake.
- Step 5: Refrigerate at 36–46°F (2–8°C). Use within 4–6 weeks.
Use the dosing calculator to calculate your exact concentration (mcg per unit) and how many units to draw on your syringe.
Frequently Asked Questions
How does Ipamorelin work? ▾
Ipamorelin is a pentapeptide that selectively mimics ghrelin and binds to the growth hormone secretagogue receptor (GHS-R) in the pituitary gland. Unlike other GHRPs, it produces a very targeted GH release without significantly elevating cortisol, acetylcholine, prolactin, or aldosterone, resulting in fewer side effects.
What are the key research findings? ▾
- Highly selective GH release with minimal impact on other hormones
- Shown to increase bone mineral density and lean body mass in studies
- Research suggests improved recovery and sleep quality
- Often studied in combination with CJC-1295 for synergistic GH release
What is the typical dosing protocol? ▾
Beginner dosing typically starts at 100 mcg subcutaneously 1–2 times daily (morning and/or before bed). Intermediate protocols use 200–300 mcg 2–3 times daily. Commonly stacked with CJC-1295 (no DAC) for enhanced GH pulsatility. Cycles typically run 8–12 weeks.
How should Ipamorelin be stored? ▾
Unreconstituted powder should be stored in a freezer or refrigerator away from light and moisture. Once reconstituted with bacteriostatic water, refrigerate at 36–46°F (2–8°C) and use within 4–6 weeks. Never freeze reconstituted peptides.