How It Works
Fragment 176-191 is a stabilized peptide fragment from the C-terminal region of growth hormone. It stimulates lipolysis (fat breakdown) by activating hormone-sensitive lipase in adipocytes and inhibits lipogenesis (new fat formation). Unlike full HGH, it does not compete for HGH receptors and does not affect IGF-1 levels or blood glucose.
Key Research Findings
- 12.5x more potent for fat loss than full-length HGH in studies
- Does not affect blood sugar levels or promote insulin resistance
- Specific to fat metabolism without anabolic effects on other tissues
- May support cartilage regeneration in addition to fat loss
Common Research Protocols
Use our free dosing calculator to determine exact syringe units after reconstitution.
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Shop Valor Sciences →Reconstitution Guide
Follow these steps to properly reconstitute Fragment 176-191 (HGH Frag) for research use:
- Step 1: Swab the tops of both the peptide vial and bacteriostatic water vial with alcohol.
- Step 2: Draw your desired amount of BAC water (commonly 1–2 mL) into an insulin syringe.
- Step 3: Inject the water slowly into the peptide vial, aiming at the glass wall — not directly onto the powder.
- Step 4: Swirl the vial gently until fully dissolved — never shake.
- Step 5: Refrigerate at 36–46°F (2–8°C). Use within 4–6 weeks.
Use the dosing calculator to calculate your exact concentration (mcg per unit) and how many units to draw on your syringe.
Frequently Asked Questions
- 12.5x more potent for fat loss than full-length HGH in studies
- Does not affect blood sugar levels or promote insulin resistance
- Specific to fat metabolism without anabolic effects on other tissues
- May support cartilage regeneration in addition to fat loss
Need to Calculate Your Fragment 176-191 (HGH Frag) Dose?
Use our free reconstitution calculator for precise syringe measurements.
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