How It Works
Dihexa (N-hexanoic-Tyr-Ile-(6) aminohexanoic amide) is a small peptide that activates hepatocyte growth factor (HGF) receptor c-Met in the brain. This promotes dendritic spine formation and synaptogenesis — literally creating new neural connections. It enhances synaptic plasticity and may rescue cognitive function in models of neurodegeneration.
Reconstitution Guide
Follow these steps to properly reconstitute Dihexa for research use:
- Step 1: Swab the tops of both the peptide vial and bacteriostatic water vial with alcohol.
- Step 2: Draw your desired amount of BAC water (commonly 1–2 mL) into an insulin syringe.
- Step 3: Inject the water slowly into the peptide vial, aiming at the glass wall — not directly onto the powder.
- Step 4: Swirl the vial gently until fully dissolved — never shake.
- Step 5: Refrigerate at 36–46°F (2–8°C). Use within 4–6 weeks.
Use the dosing calculator to calculate your exact concentration (mcg per unit) and how many units to draw on your syringe.
Frequently Asked Questions
How does Dihexa work? ▾
Dihexa (N-hexanoic-Tyr-Ile-(6) aminohexanoic amide) is a small peptide that activates hepatocyte growth factor (HGF) receptor c-Met in the brain. This promotes dendritic spine formation and synaptogenesis — literally creating new neural connections. It enhances synaptic plasticity and may rescue cognitive function in models of neurodegeneration.
What are the key research findings? ▾
- Up to 10 million times more potent than BDNF at promoting new synaptic connections
- Restored cognitive function in scopolamine-impaired animal models
- Promotes neurogenesis and dendritic spine growth in the hippocampus
- Crosses the blood-brain barrier when administered orally or subcutaneously
What is the typical dosing protocol? ▾
Oral dosing: 10–20 mg once daily. Subcutaneous dosing is also studied at lower doses. Cycles typically run 2–4 weeks due to the compound's extreme potency. This is a very novel research compound with limited long-term human data — approach with caution and consult current literature.
How should Dihexa be stored? ▾
Unreconstituted powder should be stored in a freezer or refrigerator away from light and moisture. Once reconstituted with bacteriostatic water, refrigerate at 36–46°F (2–8°C) and use within 4–6 weeks. Never freeze reconstituted peptides.