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Dihexa

Cognitive Neuroprotective
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How It Works

Dihexa (N-hexanoic-Tyr-Ile-(6) aminohexanoic amide) is a small peptide that activates hepatocyte growth factor (HGF) receptor c-Met in the brain. This promotes dendritic spine formation and synaptogenesis — literally creating new neural connections. It enhances synaptic plasticity and may rescue cognitive function in models of neurodegeneration.

Key Research Findings

Common Research Protocols

Research Dosing Range
Oral dosing: 10–20 mg once daily. Subcutaneous dosing is also studied at lower doses. Cycles typically run 2–4 weeks due to the compound's extreme potency. This is a very novel research compound with limited long-term human data — approach with caution and consult current literature.

Use our free dosing calculator to determine exact syringe units after reconstitution.

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Reconstitution Guide

Follow these steps to properly reconstitute Dihexa for research use:

Use the dosing calculator to calculate your exact concentration (mcg per unit) and how many units to draw on your syringe.

Frequently Asked Questions

How does Dihexa work?
Dihexa (N-hexanoic-Tyr-Ile-(6) aminohexanoic amide) is a small peptide that activates hepatocyte growth factor (HGF) receptor c-Met in the brain. This promotes dendritic spine formation and synaptogenesis — literally creating new neural connections. It enhances synaptic plasticity and may rescue cognitive function in models of neurodegeneration.
What are the key research findings?
  • Up to 10 million times more potent than BDNF at promoting new synaptic connections
  • Restored cognitive function in scopolamine-impaired animal models
  • Promotes neurogenesis and dendritic spine growth in the hippocampus
  • Crosses the blood-brain barrier when administered orally or subcutaneously
What is the typical dosing protocol?
Oral dosing: 10–20 mg once daily. Subcutaneous dosing is also studied at lower doses. Cycles typically run 2–4 weeks due to the compound's extreme potency. This is a very novel research compound with limited long-term human data — approach with caution and consult current literature.
How should Dihexa be stored?
Unreconstituted powder should be stored in a freezer or refrigerator away from light and moisture. Once reconstituted with bacteriostatic water, refrigerate at 36–46°F (2–8°C) and use within 4–6 weeks. Never freeze reconstituted peptides.

Need to Calculate Your Dihexa Dose?

Use our free reconstitution calculator for precise syringe measurements.

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