How It Works
Tesamorelin is a synthetic growth hormone-releasing hormone (GHRH) analog that acts on pituitary somatotroph cells to stimulate the production and secretion of endogenous growth hormone. Unlike exogenous GH, it maintains the body's natural pulsatile release pattern and negative feedback loops.
Key Research Findings
- FDA-approved for reduction of visceral adipose tissue (VAT)
- Shown to improve body composition with reduced trunk fat in clinical trials
- Research suggests improvements in IGF-1 levels and lipid profiles
- Studies indicate potential cognitive benefits and improved cardiovascular markers
Common Research Protocols
Research Dosing Range
Standard clinical dosing is 2 mg administered subcutaneously once daily, typically before bed or in the morning on an empty stomach. Research protocols commonly run 12–26 weeks. Some protocols use lower doses of 1 mg daily.
Use our free dosing calculator to determine exact syringe units after reconstitution.
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Shop Valor Sciences →Reconstitution Guide
Follow these steps to properly reconstitute Tesamorelin for research use:
- Step 1: Swab the tops of both the peptide vial and bacteriostatic water vial with alcohol.
- Step 2: Draw your desired amount of BAC water (commonly 1–2 mL) into an insulin syringe.
- Step 3: Inject the water slowly into the peptide vial, aiming at the glass wall — not directly onto the powder.
- Step 4: Swirl the vial gently until fully dissolved — never shake.
- Step 5: Refrigerate at 36–46°F (2–8°C). Use within 4–6 weeks.
Use the dosing calculator to calculate your exact concentration (mcg per unit) and how many units to draw on your syringe.
Frequently Asked Questions
How does Tesamorelin work? ▾
Tesamorelin is a synthetic growth hormone-releasing hormone (GHRH) analog that acts on pituitary somatotroph cells to stimulate the production and secretion of endogenous growth hormone. Unlike exogenous GH, it maintains the body's natural pulsatile release pattern and negative feedback loops.
What are the key research findings? ▾
- FDA-approved for reduction of visceral adipose tissue (VAT)
- Shown to improve body composition with reduced trunk fat in clinical trials
- Research suggests improvements in IGF-1 levels and lipid profiles
- Studies indicate potential cognitive benefits and improved cardiovascular markers
What is the typical dosing protocol? ▾
Standard clinical dosing is 2 mg administered subcutaneously once daily, typically before bed or in the morning on an empty stomach. Research protocols commonly run 12–26 weeks. Some protocols use lower doses of 1 mg daily.
How should Tesamorelin be stored? ▾
Unreconstituted powder should be stored in a freezer or refrigerator away from light and moisture. Once reconstituted with bacteriostatic water, refrigerate at 36–46°F (2–8°C) and use within 4–6 weeks. Never freeze reconstituted peptides.
Need to Calculate Your Tesamorelin Dose?
Use our free reconstitution calculator for precise syringe measurements.
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