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MGF (Mechano Growth Factor)

Skeletal Muscle Recovery
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How It Works

MGF (IGF-1Ec) is produced by muscle cells in response to mechanical damage from exercise. It activates satellite cells — dormant muscle stem cells that fuse with existing muscle fibers to repair damage and add new nuclei for growth. Native MGF has a very short half-life (minutes), so the PEGylated form (PEG-MGF) extends activity to several days. Unlike IGF-1 LR3, MGF specifically targets local muscle repair.

Key Research Findings

Common Research Protocols

Research Dosing Range
Standard MGF: 100–200 mcg injected bilaterally into target muscles immediately post-workout. PEG-MGF: 200 mcg subcutaneously 2–3 times per week. Not typically used on the same day as IGF-1 LR3. Cycles run 4–6 weeks with equal time off.

Use our free dosing calculator to determine exact syringe units after reconstitution.

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Reconstitution Guide

Follow these steps to properly reconstitute MGF (Mechano Growth Factor) for research use:

Use the dosing calculator to calculate your exact concentration (mcg per unit) and how many units to draw on your syringe.

Frequently Asked Questions

How does MGF (Mechano Growth Factor) work?
MGF (IGF-1Ec) is produced by muscle cells in response to mechanical damage from exercise. It activates satellite cells — dormant muscle stem cells that fuse with existing muscle fibers to repair damage and add new nuclei for growth. Native MGF has a very short half-life (minutes), so the PEGylated form (PEG-MGF) extends activity to several days. Unlike IGF-1 LR3, MGF specifically targets local muscle repair.
What are the key research findings?
  • Activates satellite cells for local muscle repair and hyperplasia
  • Produced naturally in muscle tissue after resistance exercise
  • PEG-MGF extends the half-life from minutes to several days
  • May improve recovery from muscle injuries when used with rehabilitation
What is the typical dosing protocol?
Standard MGF: 100–200 mcg injected bilaterally into target muscles immediately post-workout. PEG-MGF: 200 mcg subcutaneously 2–3 times per week. Not typically used on the same day as IGF-1 LR3. Cycles run 4–6 weeks with equal time off.
How should MGF (Mechano Growth Factor) be stored?
Unreconstituted powder should be stored in a freezer or refrigerator away from light and moisture. Once reconstituted with bacteriostatic water, refrigerate at 36–46°F (2–8°C) and use within 4–6 weeks. Never freeze reconstituted peptides.

Need to Calculate Your MGF (Mechano Growth Factor) Dose?

Use our free reconstitution calculator for precise syringe measurements.

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