How It Works
MGF (IGF-1Ec) is produced by muscle cells in response to mechanical damage from exercise. It activates satellite cells — dormant muscle stem cells that fuse with existing muscle fibers to repair damage and add new nuclei for growth. Native MGF has a very short half-life (minutes), so the PEGylated form (PEG-MGF) extends activity to several days. Unlike IGF-1 LR3, MGF specifically targets local muscle repair.
Reconstitution Guide
Follow these steps to properly reconstitute MGF (Mechano Growth Factor) for research use:
- Step 1: Swab the tops of both the peptide vial and bacteriostatic water vial with alcohol.
- Step 2: Draw your desired amount of BAC water (commonly 1–2 mL) into an insulin syringe.
- Step 3: Inject the water slowly into the peptide vial, aiming at the glass wall — not directly onto the powder.
- Step 4: Swirl the vial gently until fully dissolved — never shake.
- Step 5: Refrigerate at 36–46°F (2–8°C). Use within 4–6 weeks.
Use the dosing calculator to calculate your exact concentration (mcg per unit) and how many units to draw on your syringe.
Frequently Asked Questions
How does MGF (Mechano Growth Factor) work? ▾
MGF (IGF-1Ec) is produced by muscle cells in response to mechanical damage from exercise. It activates satellite cells — dormant muscle stem cells that fuse with existing muscle fibers to repair damage and add new nuclei for growth. Native MGF has a very short half-life (minutes), so the PEGylated form (PEG-MGF) extends activity to several days. Unlike IGF-1 LR3, MGF specifically targets local muscle repair.
What are the key research findings? ▾
- Activates satellite cells for local muscle repair and hyperplasia
- Produced naturally in muscle tissue after resistance exercise
- PEG-MGF extends the half-life from minutes to several days
- May improve recovery from muscle injuries when used with rehabilitation
What is the typical dosing protocol? ▾
Standard MGF: 100–200 mcg injected bilaterally into target muscles immediately post-workout. PEG-MGF: 200 mcg subcutaneously 2–3 times per week. Not typically used on the same day as IGF-1 LR3. Cycles run 4–6 weeks with equal time off.
How should MGF (Mechano Growth Factor) be stored? ▾
Unreconstituted powder should be stored in a freezer or refrigerator away from light and moisture. Once reconstituted with bacteriostatic water, refrigerate at 36–46°F (2–8°C) and use within 4–6 weeks. Never freeze reconstituted peptides.