How do I reconstitute Kisspeptin?

Add bacteriostatic water slowly to the vial, aiming at the glass wall. Swirl gently until dissolved. Use the TheDoseGuide free dosing calculator to determine your exact concentration and syringe units.

Kisspeptin — Dosing, Research & Reconstitution Guide

How It Works

Kisspeptin (encoded by the KISS1 gene) binds to GPR54 (KISS1R) receptors on GnRH neurons in the hypothalamus, triggering the release of gonadotropin-releasing hormone (GnRH). This cascade stimulates the pituitary to release LH (luteinizing hormone) and FSH (follicle-stimulating hormone), which regulate testosterone production, ovulation, and fertility.

Key Research Findings

Identified as the "master switch" of puberty onset and reproductive function
Rapidly stimulates LH and testosterone release in healthy males
Studied as a trigger for egg maturation in IVF protocols as an alternative to HCG
Research exploring roles in libido, metabolic health, and mood regulation

Common Research Protocols

Research Dosing Range

Clinical studies use intravenous or subcutaneous administration of kisspeptin-10 or kisspeptin-54 at varying doses. This is primarily a clinical research compound with limited established self-administration protocols. Consult current literature for the latest dosing guidance.

Use our free dosing calculator to determine exact syringe units after reconstitution.

Reconstitution Guide

Follow these steps to properly reconstitute Kisspeptin for research use:

Step 1: Swab the tops of both the peptide vial and bacteriostatic water vial with alcohol.
Step 2: Draw your desired amount of BAC water (commonly 1–2 mL) into an insulin syringe.
Step 3: Inject the water slowly into the peptide vial, aiming at the glass wall — not directly onto the powder.
Step 4: Swirl the vial gently until fully dissolved — never shake.
Step 5: Refrigerate at 36–46°F (2–8°C). Use within 4–6 weeks.

Use the dosing calculator to calculate your exact concentration (mcg per unit) and how many units to draw on your syringe.

Frequently Asked Questions

How does Kisspeptin work? ▾

Kisspeptin (encoded by the KISS1 gene) binds to GPR54 (KISS1R) receptors on GnRH neurons in the hypothalamus, triggering the release of gonadotropin-releasing hormone (GnRH). This cascade stimulates the pituitary to release LH (luteinizing hormone) and FSH (follicle-stimulating hormone), which regulate testosterone production, ovulation, and fertility.

What are the key research findings? ▾

Identified as the "master switch" of puberty onset and reproductive function
Rapidly stimulates LH and testosterone release in healthy males
Studied as a trigger for egg maturation in IVF protocols as an alternative to HCG
Research exploring roles in libido, metabolic health, and mood regulation

What is the typical dosing protocol? ▾

Clinical studies use intravenous or subcutaneous administration of kisspeptin-10 or kisspeptin-54 at varying doses. This is primarily a clinical research compound with limited established self-administration protocols. Consult current literature for the latest dosing guidance.

How should Kisspeptin be stored? ▾

Unreconstituted powder should be stored in a freezer or refrigerator away from light and moisture. Once reconstituted with bacteriostatic water, refrigerate at 36–46°F (2–8°C) and use within 4–6 weeks. Never freeze reconstituted peptides.

Kisspeptin

How It Works

Key Research Findings

Common Research Protocols

Reconstitution Guide

Frequently Asked Questions

Need to Calculate Your Kisspeptin Dose?

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